NRx ORAC-15,000™ High Potency Antioxidant - 500mg 60 Caps
15,000 (μmol TE/g) ORAC Value
Botanical source: The seed, skin and fruit of Grape (Vitis
vinifera)
Highest known ORAC value supplement ingredient
Adds significant
anti-oxidant activity to any supplement or beverage
Supports cardiovascular
health
Excellent water solubility
and mild flavor for beverage applications
Product Description:
ORAC-15,000™ is a unique and highly
concentrated extract of grape skin, seed and fruit. The extract is naturally
rich in proanthocyanidins (a group of phenolic compounds) also called OPC’s.
These compounds contribute to the antioxidant potential and are concentrated to
a levels which makes ORAC-15,000™ the highest known ORAC value ingredient (a
comparison of ORAC value substances is shown below, Table 1 [1-3]).
ORAC value and anti-oxidant capacity:
ORAC, the Oxygen Radical Absorbance
Capacity system was developed by the USDA to reliably quantify the anti-oxidant
capacity of foods and supplement compounds. ORAC is reported in Trolox
Equivalents (TE), per one gram of product tested. Trolox is a watersoluble
vitamin-E like compound that is used as a standard.
Pharmacology and Clinicals:
The compounds in ORAC-15,000™ from grape
extract are potent antioxidants [5]. They strengthen and protect cell membranes
from oxidative damage, provide cardiovascular support and wide ranging health
benefits [6].
Analytical
Specifications: The antioxidant
capacity of ORAC-15,000™ is assured by the ORAC (APPH) method, and a value of
NLT 15,000 ORAC value is guaranteed. ORAC-15,000™ is also required to pass each
step of the Ethical Naturals ProfileProven™ Quality Assurance system which
guarantees product purity, potency and integrity.
Recommended Dosage:
Recommended ORAC intake (USDA) is
around 5,000 units/day, though it is estimated that most people consume less
than 3,000 units/day. To achieve 100% of the USDA recommended daily level of
ORAC antioxidant, a dose level of 350mg provides a little over 5000 ORAC units
[4].
SUPPLEMENT FACTS
Serving Size: 2
Capsules
Servings Per Container: 30 |
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Amount Per Serving |
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%
Daily Value |
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ORAC-15,000™ Grape Extract
(15,000 ORAC Value (µmol TE/g) |
1,000 mg |
>280% |
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*Daily value not established. |
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Suggested Use: Take (1)
capsule, once or twice daily, with a glass of water.
Shelf Life and Storage: 3 years at room temperature, in a cool and
low humidity
(< 55%) environment, away from direct light.
Remarks:
Extracted by food grade ethanol and distilled water with an extract ratio of
50:1; no excipients or carriers used; non-GMO; ETO-free and non-irradiated.
(*) Representative sample derived from drums of each lot, using the 'square root
of N + 1' method
(ENI.SOP.E502.7.2). Assay verified at an FDA Registered lab (ENI.SOP.H804.7.1).
(**) Verified by skip lot testing at an FDA Registered lab in accordance with
ENI testing protocol
(ENI.SOP.H804.7.2).
(***) In compliance with California Proposition 65 (< 0.5 μg/day) based on the
typical daily recommendation of 200-300 mg/day based on daily intake of 3000 to
5000 ORAC score.
Please note: Actual results may vary ± 5% to the specifications due to
laboratory test variability.
References:
[1] Prior, R.L., et al. (1999). Variability in dietary antioxidant related
natural products supplements: the need for method standardization. JANA, 2,
46-56.
[2] Cao, G., et al. (1996). Antioxidant capacity of tea and common vegetables.
J. Agri. Food Chem,
44, 3246-31.
[3] Wang, H. et al. (1996). Total antioxidant capacity of fruits.
J. Agric. Food Chem
44, 701-5.
[4] Mary J. Feeney (2004). Fruits and the prevention of lifestyle-related
disease. Clinical and
Experimental Pharmacology and Physiology, 31 (s2), S11–S13.
[5] M. Balu et al., Rejuvenation of antioxidant system in central nervous system
of aged rats by grape seed extract, Neuro Sci Lett., 383 (3), 295-300, 2005.
[6] D. Bagchi et al., Free radicals and grape seed proanthocyanidin extract:
importance in human health and disease prevention, Toxicology, 148 (2-3),
187-97, 2000.
Table1. ORAC Scores
of some common dietary supplement products, vegetables and fruits.
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